Are you a Pharmacy Student or a Pharmacist and getting bored by doing the same calculation to determine the cumulative % drug release of any dosage form? Then no more worries here we presenting The Cumulative % Drug Release Calculator which will do all the lengthy calculations for you. You just need to simply put the required values like Time, Absorbance, Slope and Intercept Values of the Standard Curve or Calibration Curve, Drug Dose etc and our tool will automatically calculate the drug release with an accuracy of 99% for you. Why wait use the tool below.
Online Cumulative % Drug Release Calculator
Time (min) | Concentration (μg/mL) | Concentration (mg/mL) | Concentration after Dilution | Amount of Drug in Sample (mg) | Amount of Drug in Dissolution Media (mg) | Cumulative % Drug Release |
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How to Use Cumulative % Drug Release Calculator
Still confused about how to use the tool no fear here is the simplified tutorial for you step by step
- Slope: In the slope box, you have to put the slope of the linearity equation of the Standard Curve of the Calibration curve of your drug. Suppose your linearity equation is like y=0.026x+0.028 then you just need to simply put 0.026 in this box. If your linearity equation is y=-0.026x+0.028 then put -0.026.
- Intercept: In the intercept box, you have to put the intercept value of the linearity equation of the Standard Curve of the Calibration curve of your drug. Suppose your linearity equation is like y=0.026x+0.028 then you just need to simply put 0.028 in this box. If your linearity equation is y=0.026x-0.028 then put -0.028.
- Absorbance: Put the absorbance values of your samples here. If you have more than one absorbance value of your samples then simply add a comma between them. Like 0,0.100,0.200,0.300.
- Time (in mins): In this box put the different time intervals in which you have withdrawn the sample to check the absorbance. Use multiple values separated by a comma. Like 0,30,60,90.
- Amount of Samples taken (mL): Amount of samples taken in the number of samples you withdraw at every time interval.
- Amount of Dissolution Media (mL): The amount of dissolution media is the total amount of dissolution media you take in the vessels of your dissolution testing apparatus. Usually, 900ml of dissolution media is taken.
- Dilution Factor: The dilution Factor is the number of times you diluted the sample to get the absorbance value. If you did not dilute the sample then take the dilution factor as 1 for each of the absorbance values. Suppose you have 3 absorbances and you did not dilute the sample then the Dilution Factor will be 1,1,1.
- Drug Dose (in mg): Drug dose is the amount of drug present in the dosage form.